Investigating Genetic Overlap between Alzheimer’s Disease, Lipids, and Coronary Artery Disease: A Large-Scale Genome-Wide Cross Trait Analysis

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Investigating Genetic Overlap between Alzheimer’s Disease, Lipids, and Coronary Artery Disease: A Large-Scale Genome-Wide Cross Trait Analysis

There is evidence to support a link between abnormal lipid metabolism and Alzheimer’s disease (AD) risk. Similarly, observational studies suggest a comorbid relationship between AD and coronary artery disease (CAD). However, the intricate biological mechanisms of AD are poorly understood, and its re...

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Bibliographic Details
Main Authors:	Kirby, A., Porter, T., Adewuyi, Emmanuel, Laws, S.M.
Format:	Journal Article
Language:	English
Published:	2024
Subjects:	Alzheimer’s disease Mendelian randomisation coronary artery disease gene-based analysis global genetic correlation linkage disequilibrium score regression lipids local analysis of [co]variant associations local genetic correlation Humans Alzheimer Disease Coronary Artery Disease Genome-Wide Association Study Genetic Predisposition to Disease Lipids Lipid Metabolism Quantitative Trait Loci Polymorphism, Single Nucleotide Triglycerides
Online Access:	http://hdl.handle.net/20.500.11937/97665

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