Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin

Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin

Benzodiazepine (BDZ) is generally thought to bind to site II of human serum albumin (HSA), also known as the indole-BDZ site, which is located at subdomain III A of the molecule. However, differences in the binding characteristics of BDZ drugs with HSA have been reported. The photolabeling profiles...

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Bibliographic Details
Main Authors: Chuang, Victor, Otagiri, M.
Format: Journal Article
Published: Elsevier 2001
Subjects:
Flunitrazepam
Human serum albumin
Benzodiazepine
Fatty acid
Binding site
Photoa¤nity labeling
Online Access:http://hdl.handle.net/20.500.11937/9584

Internet

http://hdl.handle.net/20.500.11937/9584

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