Understanding the underlying mechanisms behind macrophage dysfunction in the elderly tumour microenvironment

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Understanding the underlying mechanisms behind macrophage dysfunction in the elderly tumour microenvironment

Cancer incidence increases with age which coincides with changes to immune cells, called macrophages. This thesis identified macrophages become dysregulated with ageing to promote tumour growth. Intracellular communication molecules, called mTOR, drive this process and targeting mTOR led to a signif...

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Bibliographic Details
Main Author:	Duong, Lelinh
Format:	Thesis
Published:	Curtin University 2023
Online Access:	http://hdl.handle.net/20.500.11937/95642

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