Understanding the underlying mechanisms behind macrophage dysfunction in the elderly tumour microenvironment
Cancer incidence increases with age which coincides with changes to immune cells, called macrophages. This thesis identified macrophages become dysregulated with ageing to promote tumour growth. Intracellular communication molecules, called mTOR, drive this process and targeting mTOR led to a signif...
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| Format: | Thesis |
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Curtin University
2023
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| Online Access: | http://hdl.handle.net/20.500.11937/95642 |