Albumin-drug interaction and its clinical implication

Background: Human serum albumin acts as a reservoir and transport protein for endogenous (e.g. fatty acids or bilirubin) and exogenous compounds (e.g. drugs or nutrients) in the blood. The binding of a drug to albumin is a major determinant of its pharmacokinetic and pharmacodynamic profile.Scope of...

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Bibliographic Details
Main Authors: Yamasaki, K., Maruyama, T., Chuang, Victor, Otagiri, M.
Format: Journal Article
Published: Elsevier BV 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/9478