Mitochondrial gene expression is required for platelet function and blood clotting

Mitochondrial gene expression is required for platelet function and blood clotting

Platelets are anucleate blood cells that contain mitochondria and regulate blood clotting in response to injury. Mitochondria contain their own gene expression machinery that relies on nuclear-encoded factors for the biogenesis of the oxidative phosphorylation system to produce energy required for t...

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Bibliographic Details
Main Authors: Richman, T.R., Ermer, J.A., Baker, J., Siira, S.J., Kile, B.T., Linden, M.D., Rackham, Oliver, Filipovska, A.
Format: Journal Article
Language:English
Published: 2023
Subjects:
CP: Immunology
megakaryocytes
mitochondria
mitochondrial gene expression
platelets
translation
Humans
Genes, Mitochondrial
Proteomics
Hemostasis
Blood Coagulation
Blood Platelets
Megakaryocytes
Thrombosis
Gene Expression
Mitochondrial Proteins
Online Access:http://purl.org/au-research/grants/arc/DP180101656
http://hdl.handle.net/20.500.11937/94737

Internet

http://purl.org/au-research/grants/arc/DP180101656
http://hdl.handle.net/20.500.11937/94737

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