A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate
3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), a furan fatty acid uremic toxin (UT) and a substrate for organic ion transporters, contributes to the accumulation of CMPF in renal tubular cells. Although oxidative stress induced by UTs has been proposed as a mechanism of its toxicity in chroni...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/9424 |