Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population

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Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population

Background and Purpose: Polygenic risk scores (PRSs) can be used to predict ischemic stroke (IS). However, further validation of PRS performance is required in independent populations, particularly older adults in whom the majority of strokes occur. Methods: We predicted risk of incident IS events i...

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Bibliographic Details
Main Authors:	Neumann, J.T., Riaz, M., Bakshi, A., Polekhina, G., Thao, L.T.P., Nelson, M.R., Woods, R.L., Abraham, G., Inouye, M., Reid, Christopher, Tonkin, A.M., Williamson, J.D., Donnan, G.A., Brodtmann, A., Cloud, G.C., McNeil, J.J., Lacaze, P.
Format:	Journal Article
Language:	English
Published:	LIPPINCOTT WILLIAMS & WILKINS 2021
Subjects:	Science & Technology Life Sciences & Biomedicine Clinical Neurology Peripheral Vascular Disease Neurosciences & Neurology Cardiovascular System & Cardiology aged area under curve dementia risk factors stroke PREVENTION Aged Aged, 80 and over Brain Ischemia Female Humans Ischemic Stroke Male Middle Aged Proportional Hazards Models Risk Assessment Risk Factors Stroke
Online Access:	http://purl.org/au-research/grants/nhmrc/1136372 http://hdl.handle.net/20.500.11937/93093

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