Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population

Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population

Background and Purpose: Polygenic risk scores (PRSs) can be used to predict ischemic stroke (IS). However, further validation of PRS performance is required in independent populations, particularly older adults in whom the majority of strokes occur. Methods: We predicted risk of incident IS events i...

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Bibliographic Details
Main Authors: Neumann, J.T., Riaz, M., Bakshi, A., Polekhina, G., Thao, L.T.P., Nelson, M.R., Woods, R.L., Abraham, G., Inouye, M., Reid, Christopher, Tonkin, A.M., Williamson, J.D., Donnan, G.A., Brodtmann, A., Cloud, G.C., McNeil, J.J., Lacaze, P.
Format: Journal Article
Language:English
Published: LIPPINCOTT WILLIAMS & WILKINS 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Clinical Neurology
Peripheral Vascular Disease
Neurosciences & Neurology
Cardiovascular System & Cardiology
aged
area under curve
dementia
risk factors
stroke
PREVENTION
Aged
Aged, 80 and over
Brain Ischemia
Female
Humans
Ischemic Stroke
Male
Middle Aged
Proportional Hazards Models
Risk Assessment
Risk Factors
Stroke
Online Access:http://purl.org/au-research/grants/nhmrc/1136372
http://hdl.handle.net/20.500.11937/93093

Internet

http://purl.org/au-research/grants/nhmrc/1136372
http://hdl.handle.net/20.500.11937/93093

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