Therapeutic potential of coumestan pks13 inhibitors for tuberculosis

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Therapeutic potential of coumestan pks13 inhibitors for tuberculosis

Polyketide synthase 13 (Pks13) is an important enzyme found in Mycobacterium tuberculosis that condenses two fatty acyl chains to produce a-alkyl b-ketoesters, which in turn serve as the precursors for the synthesis of mycolic acids that are essential building blocks for maintaining the cell wall in...

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Bibliographic Details
Main Authors:	Lun, S., Xiao, S., Zhang, W., Wang, S., Gunosewoyo, Hendra, Yu, L.F., Bishai, W.R.
Format:	Journal Article
Language:	English
Published:	AMER SOC MICROBIOLOGY 2021
Subjects:	Science & Technology Life Sciences & Biomedicine Microbiology Pharmacology & Pharmacy chemotherapy Mycobacterium tuberculosis Pks13 inhibitor mouse model MYCOLIC ACID BIOSYNTHESIS CATALYZES ENVELOPE PATHWAY TARGET
Online Access:	http://purl.org/au-research/grants/arc/DE160100482 http://hdl.handle.net/20.500.11937/90997

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