Therapeutic potential of coumestan pks13 inhibitors for tuberculosis

Therapeutic potential of coumestan pks13 inhibitors for tuberculosis

Polyketide synthase 13 (Pks13) is an important enzyme found in Mycobacterium tuberculosis that condenses two fatty acyl chains to produce a-alkyl b-ketoesters, which in turn serve as the precursors for the synthesis of mycolic acids that are essential building blocks for maintaining the cell wall in...

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Bibliographic Details
Main Authors: Lun, S., Xiao, S., Zhang, W., Wang, S., Gunosewoyo, Hendra, Yu, L.F., Bishai, W.R.
Format: Journal Article
Language:English
Published: AMER SOC MICROBIOLOGY 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Microbiology
Pharmacology & Pharmacy
chemotherapy
Mycobacterium tuberculosis
Pks13 inhibitor
mouse model
MYCOLIC ACID BIOSYNTHESIS
CATALYZES
ENVELOPE
PATHWAY
TARGET
Online Access:http://purl.org/au-research/grants/arc/DE160100482
http://hdl.handle.net/20.500.11937/90997

Internet

http://purl.org/au-research/grants/arc/DE160100482
http://hdl.handle.net/20.500.11937/90997

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