Building artificial genetic circuits to understand protein function

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Building artificial genetic circuits to understand protein function

Intrinsic protein properties that may not be apparent by only examining three-dimensional structures can be revealed by careful analysis of mutant protein variants. Deep mutational scanning is a technique that allows the functional analysis of millions of protein variants in a single experiment. To...

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Bibliographic Details
Main Authors:	Scott, L.H., Mathews, J.C., Filipovska, A., Rackham, Oliver
Other Authors:	Shukla, AK
Format:	Book Chapter
Language:	English
Published:	ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD 2020
Subjects:	Science & Technology Life Sciences & Biomedicine Biochemical Research Methods Biochemistry & Molecular Biology Cell Biology YEAST RESISTANCE PARALLEL TOOLKIT SYSTEM TRANSFORMATION RECOGNITION TIGECYCLINE EXPRESSION EFFICIENCY Antibiotic resistance Biosensor Deep mutational scanning Genetic circuit Structure-function relationship Synthetic biology Gene Regulatory Networks Mutant Proteins Mutation Proteins Saccharomyces cerevisiae
Online Access:	https://research-repository.uwa.edu.au/files/81276020/Scott_et_al._Author_Manuscript.pdf http://hdl.handle.net/20.500.11937/90960

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