Building artificial genetic circuits to understand protein function

Building artificial genetic circuits to understand protein function

Intrinsic protein properties that may not be apparent by only examining three-dimensional structures can be revealed by careful analysis of mutant protein variants. Deep mutational scanning is a technique that allows the functional analysis of millions of protein variants in a single experiment. To...

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Bibliographic Details
Main Authors: Scott, L.H., Mathews, J.C., Filipovska, A., Rackham, Oliver
Other Authors: Shukla, AK
Format: Book Chapter
Language:English
Published: ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD 2020
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemical Research Methods
Biochemistry & Molecular Biology
Cell Biology
YEAST
RESISTANCE
PARALLEL
TOOLKIT
SYSTEM
TRANSFORMATION
RECOGNITION
TIGECYCLINE
EXPRESSION
EFFICIENCY
Antibiotic resistance
Biosensor
Deep mutational scanning
Genetic circuit
Structure-function relationship
Synthetic biology
Gene Regulatory Networks
Mutant Proteins
Mutation
Proteins
Saccharomyces cerevisiae
Online Access:https://research-repository.uwa.edu.au/files/81276020/Scott_et_al._Author_Manuscript.pdf
http://hdl.handle.net/20.500.11937/90960

Internet

https://research-repository.uwa.edu.au/files/81276020/Scott_et_al._Author_Manuscript.pdf
http://hdl.handle.net/20.500.11937/90960

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