Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins

DNA is typically found as a double helix, however it must be separated into single strands during all phases of DNA metabolism; including transcription, replication, recombination and repair. Although recent breakthroughs have enabled the design of modular RNA- and double-stranded DNA-binding protei...

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Bibliographic Details
Main Authors: Spåhr, H., Chia, T., Lingford, J.P., Siira, S.J., Cohen, S.B., Filipovska, A., Rackham, Oliver
Format: Journal Article
Language:English
Published: NATURE PUBLISHING GROUP 2018
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
SINGLE-STRANDED RNA
STRUCTURAL BASIS
PENTATRICOPEPTIDE
RECOGNITION
MODEL
POT1
IDENTIFICATION
EXTENSION
PATTERNS
SEQUENCE
Online Access:http://purl.org/au-research/grants/arc/DP180101656
http://hdl.handle.net/20.500.11937/90820

Internet

http://purl.org/au-research/grants/arc/DP180101656
http://hdl.handle.net/20.500.11937/90820

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