Design, synthesis and evaluation of novel indole-2-carboxamides for growth inhibition of Mycobacterium tuberculosis and paediatric brain tumour cells

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Design, synthesis and evaluation of novel indole-2-carboxamides for growth inhibition of Mycobacterium tuberculosis and paediatric brain tumour cells

The omnipresent threat of tuberculosis (TB) and the scant treatment options thereof necessitate the development of new antitubercular agents, preferably working via a novel mechanism of action distinct from the current drugs. Various studies identified the mycobacterial membrane protein large 3 tran...

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Bibliographic Details
Main Authors:	Alsayed, Shahinda S.R., Lun, S., Bailey, A.W., Suri, A., Huang, C.C., Mocerino, Mauro, Payne, Alan, Sredni, S.T., Bishai, W.R., Gunosewoyo, Hendra
Format:	Journal Article
Language:	English
Published:	ROYAL SOC CHEMISTRY 2021
Subjects:	Science & Technology Physical Sciences Chemistry, Multidisciplinary Chemistry MYCOLIC ACID TRANSPORT MEMBRANE TRANSPORTER DRUG DISCOVERY NERVOUS-SYSTEM GLIAL-CELLS ANTITUBERCULOSIS ANTICANCER RESISTANT MMPL3 ANTIMYCOBACTERIAL
Online Access:	http://purl.org/au-research/grants/arc/DE160100482 http://hdl.handle.net/20.500.11937/90753

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