Construction of single-chain Fv with two possible CDR3H conformations but similar inter-molecular forces that neutralize bovine herpesvirus 1

Bovine herpesvirus 1 (BoHV-1) causes respiratory and genital diseases in cattle for which available vaccines do not confer adequate protection. Since passive immunization with antibodies permits disease prevention, single-chain fragment variable (scFv), originating from a monoclonal bovine IgG1 anti...

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Bibliographic Details
Main Authors: Koti, M., Farrugia, W., Nagy, E., Ramsland, Paul, Kaushik, A.
Format: Journal Article
Published: 2010
Online Access:http://hdl.handle.net/20.500.11937/9046