Characterising murine hippocampal iron homeostasis, in relation to markers of brain inflammation and metabolism, during ageing

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Characterising murine hippocampal iron homeostasis, in relation to markers of brain inflammation and metabolism, during ageing

Metal ions (Fe, Cu, and Zn) are essential to a healthy brain function, with the amount, localisation, and chemical form often tightly controlled. Evidence points towards loss of metal ion homeostasis within the ageing brain; in particular brain Fe accumulation appears to be a hallmark of ageing, whi...

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Bibliographic Details
Main Authors:	Ellison, Gae, Duong, Lelinh, Hollings, Ashley, Howard, D., Jackaman, Connie, Hackett, Mark
Format:	Journal Article
Language:	English
Published:	OXFORD UNIV PRESS 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology mapping memory dementia XFM XRF FTIR multimodal microscopy FIBRILLARY ACIDIC PROTEIN ZINC-DEFICIENCY AMYLOID-BETA FERROUS IRON SUBSTANTIA-NIGRA OXIDATIVE STRESS RAT HIPPOCAMPUS PERFUSION-PERLS MOUSE-BRAIN GLIAL-CELLS
Online Access:	http://purl.org/au-research/grants/arc/FT190100017 http://hdl.handle.net/20.500.11937/90109

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