Characterising murine hippocampal iron homeostasis, in relation to markers of brain inflammation and metabolism, during ageing

Characterising murine hippocampal iron homeostasis, in relation to markers of brain inflammation and metabolism, during ageing

Metal ions (Fe, Cu, and Zn) are essential to a healthy brain function, with the amount, localisation, and chemical form often tightly controlled. Evidence points towards loss of metal ion homeostasis within the ageing brain; in particular brain Fe accumulation appears to be a hallmark of ageing, whi...

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Bibliographic Details
Main Authors: Ellison, Gae, Duong, Lelinh, Hollings, Ashley, Howard, D., Jackaman, Connie, Hackett, Mark
Format: Journal Article
Language:English
Published: OXFORD UNIV PRESS 2022
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
mapping
memory
dementia
XFM
XRF
FTIR
multimodal
microscopy
FIBRILLARY ACIDIC PROTEIN
ZINC-DEFICIENCY
AMYLOID-BETA
FERROUS IRON
SUBSTANTIA-NIGRA
OXIDATIVE STRESS
RAT HIPPOCAMPUS
PERFUSION-PERLS
MOUSE-BRAIN
GLIAL-CELLS
Online Access:http://purl.org/au-research/grants/arc/FT190100017
http://hdl.handle.net/20.500.11937/90109

Internet

http://purl.org/au-research/grants/arc/FT190100017
http://hdl.handle.net/20.500.11937/90109

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