Purine isosters in design and development of novel xanthin oxidase inhibitors

This research focuses on the discovery of novel inhibitors of the enzyme xanthine oxidase to assist in the treatment of hyperuricemia and gout. Four different libraries of compounds with a total of 95 molecules were synthesized, purified, characterized and tested in-vitro, with additional molecular...

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Bibliographic Details
Main Author: Luna, Giuseppe
Format: Thesis
Published: Curtin University 2022
Online Access:http://hdl.handle.net/20.500.11937/89687