Sequencing directly from clinical specimens reveals genetic variations in HCMV-encoded chemokine receptor us28 that may influence antibody levels and interactions with human chemokines

Sequencing directly from clinical specimens reveals genetic variations in HCMV-encoded chemokine receptor us28 that may influence antibody levels and interactions with human chemokines

Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by;80% of the world’s population. Acute infections are asymptomatic in healthy individuals but generate diverse syndromes in neonates, solid organ transplant recipients, and HIV-infected individuals. The HCMV gene US28 encodes a homolog of a...

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Bibliographic Details
Main Authors: Waters, Shelley, Agostino, Mark, Lee, S., Ariyanto, I., Kresoje, N., Leary, S., Munyard, Kylie, Gaudieri, S., Gaff, J., Irish, A., Keil, A.D., Price, Patricia, Allcock, R.J.N.
Format: Journal Article
Language:English
Published: AMER SOC MICROBIOLOGY 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Microbiology
human cytomegalovirus
chemokine receptor
US28
renal transplant recipients
HIV patients
deep sequencing
HUMAN CYTOMEGALOVIRUS
HIV PATIENTS
CMV
SEROPREVALENCE
COINFECTION
CORECEPTOR
ACTIVATION
MUTATIONS
GENOTYPES
VARIANTS
Online Access:http://purl.org/au-research/grants/nhmrc/1068652
http://hdl.handle.net/20.500.11937/89468

Internet

http://purl.org/au-research/grants/nhmrc/1068652
http://hdl.handle.net/20.500.11937/89468

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