Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV

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Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV

Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by ~80% of adults world-wide. Acute infections are often asymptomatic in healthy individuals but generate diverse syndromes in neonates, renal transplant recipients (RTR), and people with HIV (PWH). The HCMV gene UL111a encodes a homolog of...

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Bibliographic Details
Main Authors:	Waters, Shelley, Lee, S., Ariyanto, I., Kresoje, N., Leary, S., Munyard, Kylie, Gaudieri, S., Irish, A., Keil, A.D., Allcock, R.J.N., Price, Patricia
Format:	Journal Article
Language:	English
Published:	MDPI 2022
Subjects:	Science & Technology Life Sciences & Biomedicine Physical Sciences Biochemistry & Molecular Biology Chemistry, Multidisciplinary Chemistry human cytomegalovirus interleukin-10 UL111a renal transplant recipients people with HIV deep sequencing HUMAN CYTOMEGALOVIRUS TRANSPLANT RECIPIENTS HUMAN INTERLEUKIN-10 HIV PATIENTS HOMOLOG HEALTH CMV SEROPREVALENCE ANTIBODIES MUTATIONS
Online Access:	http://purl.org/au-research/grants/nhmrc/1068652 http://hdl.handle.net/20.500.11937/89466

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