Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV

Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV

Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by ~80% of adults world-wide. Acute infections are often asymptomatic in healthy individuals but generate diverse syndromes in neonates, renal transplant recipients (RTR), and people with HIV (PWH). The HCMV gene UL111a encodes a homolog of...

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Bibliographic Details
Main Authors: Waters, Shelley, Lee, S., Ariyanto, I., Kresoje, N., Leary, S., Munyard, Kylie, Gaudieri, S., Irish, A., Keil, A.D., Allcock, R.J.N., Price, Patricia
Format: Journal Article
Language:English
Published: MDPI 2022
Subjects:
Science & Technology
Life Sciences & Biomedicine
Physical Sciences
Biochemistry & Molecular Biology
Chemistry, Multidisciplinary
Chemistry
human cytomegalovirus
interleukin-10
UL111a
renal transplant recipients
people with HIV
deep sequencing
HUMAN CYTOMEGALOVIRUS
TRANSPLANT RECIPIENTS
HUMAN INTERLEUKIN-10
HIV PATIENTS
HOMOLOG
HEALTH
CMV
SEROPREVALENCE
ANTIBODIES
MUTATIONS
Online Access:http://purl.org/au-research/grants/nhmrc/1068652
http://hdl.handle.net/20.500.11937/89466

Internet

http://purl.org/au-research/grants/nhmrc/1068652
http://hdl.handle.net/20.500.11937/89466

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