The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children

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The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children

Since there are inconsistent data relating to the effect of haemoglobinopathies on disposition of artemisinin antimalarial combination therapy, and none in sickle cell trait (SCT) or sickle cell disease (SCD), the aim of this study was to characterize the pharmacokinetic properties of artemether-lum...

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Bibliographic Details
Main Authors:	Sugiarto, S.R., Bwire, G.M., Moore, Brioni, Page-Sharp, Madhu, Manning, L., Batty, Kevin, Minzi, O.M.S., Ngasala, B., Davis, T.M.E., Makani, J., Salman, S.
Format:	Journal Article
Language:	English
Published:	2022
Subjects:	Artemether Children Desbutyl-lumefantrine Dihydroartemisinin Lumefantrine Population pharmacokinetics Sickle cell disease Sickle cell trait Tanzania
Online Access:	http://purl.org/au-research/grants/nhmrc/1124130 http://hdl.handle.net/20.500.11937/88952

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