The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children

The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children

Since there are inconsistent data relating to the effect of haemoglobinopathies on disposition of artemisinin antimalarial combination therapy, and none in sickle cell trait (SCT) or sickle cell disease (SCD), the aim of this study was to characterize the pharmacokinetic properties of artemether-lum...

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Bibliographic Details
Main Authors: Sugiarto, S.R., Bwire, G.M., Moore, Brioni, Page-Sharp, Madhu, Manning, L., Batty, Kevin, Minzi, O.M.S., Ngasala, B., Davis, T.M.E., Makani, J., Salman, S.
Format: Journal Article
Language:English
Published: 2022
Subjects:
Artemether
Children
Desbutyl-lumefantrine
Dihydroartemisinin
Lumefantrine
Population pharmacokinetics
Sickle cell disease
Sickle cell trait
Tanzania
Online Access:http://purl.org/au-research/grants/nhmrc/1124130
http://hdl.handle.net/20.500.11937/88952

Internet

http://purl.org/au-research/grants/nhmrc/1124130
http://hdl.handle.net/20.500.11937/88952

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