High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin g injections in ethiopian children and adults with rheumatic heart disease

High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin g injections in ethiopian children and adults with rheumatic heart disease

Introduction: Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncer-tainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection a...

Full description

Bibliographic Details
Main Authors: Ketema, E.B., Gishen, N.Z., Hailu, A., Leul, A., Hadgu, A., Hagos, K., Berhane, S., Tsega, T., Page-Sharp, Madhu, Davis, T.M.E., Moore, Brioni, Batty, Kevin, Carapetis, J., Salman, S., Manning, L.
Format: Journal Article
Language:English
Published: PUBLIC LIBRARY SCIENCE 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Infectious Diseases
Parasitology
Tropical Medicine
PROPHYLAXIS
FEVER
POPULATION
ECHOCARDIOGRAPHY
STREPTOCOCCI
PREVENTION
PREVALENCE
PATTERN
Online Access:http://hdl.handle.net/20.500.11937/88949

Internet

http://hdl.handle.net/20.500.11937/88949

Similar Items