Population pharmacokinetic study of ceftriaxone in elderly patients, using cystatin C-based estimates of renal function to account for frailty

Population pharmacokinetic study of ceftriaxone in elderly patients, using cystatin C-based estimates of renal function to account for frailty

Ceftriaxone is widely used for respiratory and urinary infections in elderly and frail patients, but there are few pharmacokinetic studies. A prospective population pharmacokinetic study of ceftriaxone in adults over 65 years old was undertaken. Dried blood spots collected at baseline (predose) and...

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Bibliographic Details
Main Authors: Tan, S.J., Cockcroft, M., Page-Sharp, Madhu, Arendts, G., Davis, T.M.E., Moore, Brioni, Batty, Kevin, Salman, S., Manning, L.
Format: Journal Article
Language:English
Published: AMER SOC MICROBIOLOGY 2020
Subjects:
Science & Technology
Life Sciences & Biomedicine
Microbiology
Pharmacology & Pharmacy
ceftriaxone
frailty
population pharmacokinetics
GLOMERULAR-FILTRATION-RATE
SERUM CREATININE
COCKCROFT-GAULT
CLEARANCE
EQUATIONS
IMPACT
PREDICTION
SIZE
Online Access:http://purl.org/au-research/grants/nhmrc/1047105
http://hdl.handle.net/20.500.11937/88948

Internet

http://purl.org/au-research/grants/nhmrc/1047105
http://hdl.handle.net/20.500.11937/88948

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