Adipose Loss and Metabolic Disease Due to Seipin Deficiency: Systemic Versus Tissue Specific Effects

This thesis aimed to understand the molecular mechanisms via which BSCL2 disruption causes metabolic disease in congenital generalised lipodystrophy type 2. The results presented provide evidence that seipin has significant roles in adipose tissue, by regulating lipolysis, but also in pancreatic ß-c...

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Bibliographic Details
Main Author: Roumane, Ahlima
Format: Thesis
Published: Curtin University 2021
Online Access:http://hdl.handle.net/20.500.11937/88906