A comprehensive study of novel microcapsules incorporating gliclazide and a permeation enhancing bile acid: hypoglycemic effect in an animal model of Type-1 diabetes

Context: Gliclazide (G) is a commonly prescribed drug for Type 2 diabetes (T2D). In a recent study, we found that when G was combined with a primary bile acid, and gavaged to an animal model of Type 1 diabetes (T1D), it exerted a hypoglycemic effect. We hypothesized this to be due to metabolic activ...

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Bibliographic Details
Main Authors: Mathavan, Sangeetha, Chen-Tan, N., Arfuso, Frank, Al-Salami, Hani
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/8874