Endotoxin removal and plasmid DNA recovery in various metal ion solutions

In this brief article, we report endotoxin precipitation using different types of metal ion in plasmid DNA purification. The work involved modification and improvement of the LAL chromogenic analysis to compensate for metal ion-LAL interaction. Results (Figs. 1 and 2) show that ZnSO4 gives an optimu...

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Bibliographic Details
Main Authors: Ongkudon, C., Danquah, Michael
Format: Journal Article
Published: Taylor and Francis 2011
Online Access:http://www.tandfonline.com/doi/full/10.1080/01496395.2011.557027
http://hdl.handle.net/20.500.11937/8774