Lamotrigine and valproate pharmacokinetics interactions in epileptic patients

Lamotrigine (LTG, 3,5-diamino-6- (2,3-dichlorphenyl)-l,2,4-triazine) is an antiepileptic drug used mainly for partial and generalized seizures. The efficacy of LTG in treating resistant partial seizures was optimized when it was combined with valproate (VPA). The aim of this study was to investigate...

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Bibliographic Details
Main Authors: Lalic, M., Cvejic, J., Popovic, J., Bozic, K., Golocorbin-Kon, S., Al-Salami, Hani, Mikov, M.
Format: Journal Article
Published: Springer France 2009
Online Access:http://hdl.handle.net/20.500.11937/8769