The role of Wnt/β-catenin signalling in the regulation of liver progenitor cell responses in non-alcoholic fatty liver disease
This study established a regulatory role for the Wnt/ß-catenin pathway in liver progenitor cells (LPCs) in cell culture and in vivo models of non-alcoholic fatty liver disease and demonstrated a significant potential for therapeutic targeting of LPCs with the Wnt inhibitor PRI-724 to inhibit chronic...
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| Format: | Thesis |
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Curtin University
2021
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| Online Access: | http://hdl.handle.net/20.500.11937/86615 |