Limited P-glycoprotein mediated efflux for anti-epileptic drugs.

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Limited P-glycoprotein mediated efflux for anti-epileptic drugs.

A variety of anti-epileptic drugs (AEDs) were tested for their ability to be transported by P-glycoprotein (P-gp) through Caco-2 monolayers using bi-directional (apical (Ap) to basolateral (Bas), and Bas to Ap) studies. Transport rates were equivalent in both directions for vigabatrin, gabapentin, p...

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Bibliographic Details
Main Authors:	Crowe, Andrew, Teoh, Y.
Format:	Journal Article
Published:	informa UK Ltd 2006
Online Access:	http://hdl.handle.net/20.500.11937/8478

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