Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.

BACKGROUND: The prognosis for high-risk childhood acute leukaemias remains dismal and established treatment protocols often cause long-term side effects in survivors. This study aims to identify more effective and safer therapeutics for these patients. METHODS: A high-throughput phenotypic scree...

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Bibliographic Details
Main Authors: Karsa, Mawar, Kosciolek, Angelika, Bongers, Angelika, Mariana, Anna, Failes, Tim, Gifford, Andrew J, Kees, Ursula R, Cheung, Laurence, Kotecha, Rishi, Arndt, Greg M, Haber, Michelle, Norris, Murray D, Sutton, Rosemary, Lock, Richard B, Henderson, Michelle J, Somers, Klaartje
Format: Journal Article
Language:English
Published: 2021
Online Access:http://purl.org/au-research/grants/nhmrc/1059804
http://hdl.handle.net/20.500.11937/83366