An in vivo pharmacological study: Variation in tissue-accumulation for the drug probucol as the result of targeted microtechnology and matrix-acrylic acid optimization and stabilization techniques

An in vivo pharmacological study: Variation in tissue-accumulation for the drug probucol as the result of targeted microtechnology and matrix-acrylic acid optimization and stabilization techniques

© 2019 Mooranian et al. Type 2 diabetes (T2D) is characterised by β-cell damage and hyperglycaemia. The lipophilic drug, probucol, has shown significant β-cell protective and potential antidiabetic effects, which were enhanced by hydrophilic bile acid incorporation using taurocholic acid and che...

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Bibliographic Details
Main Authors: Mooranian, Armin, Zamani, Nassim, Takechi, Ryu, Luna, Giuseppe, Mikov, M., Goločorbin-Kon, S., Elnashar, Magdy, Arfuso, Frank, Al-Salami, Hani
Format: Journal Article
Language:English
Published: PUBLIC LIBRARY SCIENCE 2019
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
POTENTIAL ANTIDIABETIC DRUG
BILE-ACID
INSULIN SENSITIVITY
DELIVERY
MICROENCAPSULATION
FORMULATION
MICROCAPSULES
MUSCLES
STRESS
Online Access:http://hdl.handle.net/20.500.11937/82373

Internet

http://hdl.handle.net/20.500.11937/82373

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