APOE e4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals: A cross-sectional observational study

APOE e4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals: A cross-sectional observational study

Background: Cerebrospinal fluid (CSF) biomarkers Aß1-42, t-tau and p-tau have a characteristic pattern in Alzheimer's Disease (AD). Their roles in HIV-associated neurocognitive disorder (HAND) remains unclear. Methods: Adults with chronic treated HIV disease were recruited (n = 43, aged 56.7 ±...

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Bibliographic Details
Main Authors: Cysique, L., Hewitt, T., Croitoru-Lamoury, J., Taddei, K., Martins, R., Chew, C., Davies, N., Price, Patricia, Brew, B.
Format: Journal Article
Published: BioMed Central Ltd. 2015
Online Access:http://hdl.handle.net/20.500.11937/8233

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http://hdl.handle.net/20.500.11937/8233

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