Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

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Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

© 2019, The Author(s). Injury to the central nervous system is exacerbated by secondary degeneration. Previous research has shown that a combination of orally and locally administered ion channel inhibitors following partial optic nerve injury protects the myelin sheath and preserves function in...

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Bibliographic Details
Main Authors:	Toomey, Lilian, Bartlett, C.A., Gavriel, N., McGonigle, Terence, Majimbi, Maimuna, Gopalasingam, G., Rodger, J., Fitzgerald, Melinda
Format:	Journal Article
Language:	English
Published:	NATURE RESEARCH 2019
Subjects:	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics BRAIN-BARRIER PERMEABILITY RETINAL GANGLION-CELLS RECEPTOR ANTAGONIST OXIDATIVE STRESS P2X7 RECEPTORS CEREBRAL EDEMA DRUG-DELIVERY CA2+ INFLUX HEAD-INJURY DAMAGE
Online Access:	http://purl.org/au-research/grants/nhmrc/1087114 http://hdl.handle.net/20.500.11937/81498

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