Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

© 2019, The Author(s). Injury to the central nervous system is exacerbated by secondary degeneration. Previous research has shown that a combination of orally and locally administered ion channel inhibitors following partial optic nerve injury protects the myelin sheath and preserves function in...

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Bibliographic Details
Main Authors: Toomey, Lilian, Bartlett, C.A., Gavriel, N., McGonigle, Terence, Majimbi, Maimuna, Gopalasingam, G., Rodger, J., Fitzgerald, Melinda
Format: Journal Article
Language:English
Published: NATURE RESEARCH 2019
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
BRAIN-BARRIER PERMEABILITY
RETINAL GANGLION-CELLS
RECEPTOR ANTAGONIST
OXIDATIVE STRESS
P2X7 RECEPTORS
CEREBRAL EDEMA
DRUG-DELIVERY
CA2+ INFLUX
HEAD-INJURY
DAMAGE
Online Access:http://purl.org/au-research/grants/nhmrc/1087114
http://hdl.handle.net/20.500.11937/81498

Internet

http://purl.org/au-research/grants/nhmrc/1087114
http://hdl.handle.net/20.500.11937/81498

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