An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

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An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

© 2016 The Authors. The highly restrictive blood-brain barrier (BBB) plays a critically important role in maintaining brain homeostasis and is pivotal for proper neuronal function. The BBB is currently considered the main limiting factor restricting the passage of large (up to 200 nm) intravenous...

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Bibliographic Details
Main Authors:	Smith, N.M., Gachulincova, I., Ho, D., Bailey, C., Bartlett, C.A., Norret, M., Murphy, J., Buckley, A., Rigby, P.J., House, M.J., Pierre, T.S., Fitzgerald, Melinda, Iyer, K.S., Dunlop, S.A.
Format:	Journal Article
Language:	English
Published:	NATURE PUBLISHING GROUP 2016
Subjects:	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics CENTRAL-NERVOUS-SYSTEM SECONDARY DEGENERATION IN-VIVO NEUROLOGICAL DISEASES DELIVERY INJURY CONTRIBUTE TRANSPORT IMMUNE DRUGS
Online Access:	http://purl.org/au-research/grants/nhmrc/1028681 http://hdl.handle.net/20.500.11937/81495

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