An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

© 2016 The Authors. The highly restrictive blood-brain barrier (BBB) plays a critically important role in maintaining brain homeostasis and is pivotal for proper neuronal function. The BBB is currently considered the main limiting factor restricting the passage of large (up to 200 nm) intravenous...

Full description

Bibliographic Details
Main Authors: Smith, N.M., Gachulincova, I., Ho, D., Bailey, C., Bartlett, C.A., Norret, M., Murphy, J., Buckley, A., Rigby, P.J., House, M.J., Pierre, T.S., Fitzgerald, Melinda, Iyer, K.S., Dunlop, S.A.
Format: Journal Article
Language:English
Published: NATURE PUBLISHING GROUP 2016
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
CENTRAL-NERVOUS-SYSTEM
SECONDARY DEGENERATION
IN-VIVO
NEUROLOGICAL DISEASES
DELIVERY
INJURY
CONTRIBUTE
TRANSPORT
IMMUNE
DRUGS
Online Access:http://purl.org/au-research/grants/nhmrc/1028681
http://hdl.handle.net/20.500.11937/81495

Internet

http://purl.org/au-research/grants/nhmrc/1028681
http://hdl.handle.net/20.500.11937/81495

Similar Items