Optimal probe length varies for targets with high sequence variation: Implications for probe library design for resequencing highly variable genes

Optimal probe length varies for targets with high sequence variation: Implications for probe library design for resequencing highly variable genes

© 2008 Haslam et al. Background: Sequencing by hybridisation is an effective method for obtaining large amounts of DNA sequence information at low cost. The efficiency of SBH depends on the design of the probe library to provide the maximum information for minimum cost. Long probes provide a high...

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Bibliographic Details
Main Authors: Haslam, N.J., Whiteford, N.E., Weber, G., Prügel-Bennett, A., Essex, J.W., Neylon, Cameron
Other Authors: Hall, Neil
Format: Journal Article
Language:English
Published: PUBLIC LIBRARY SCIENCE 2008
Subjects:
Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
Online Access:http://hdl.handle.net/20.500.11937/81469

Internet

http://hdl.handle.net/20.500.11937/81469

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