Advances and perspectives in computational prediction of microbial gene essentiality

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Advances and perspectives in computational prediction of microbial gene essentiality

Theminimal subset of genes required for cellular growth, survival and viability of an organismare classified as essential genes. Knowledge of essential genes gives insight into the core structure and functioning of a cell. Thismight lead tomore efficient antimicrobial drug discovery, to elucidation...

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Bibliographic Details
Main Authors:	Mobegi, Fredrick, Zomer, A., de Jonge, M.I., van Hijum, S.A.F.T.
Format:	Journal Article
Language:	English
Published:	OXFORD UNIV PRESS 2017
Subjects:	Science & Technology Life Sciences & Biomedicine Biotechnology & Applied Microbiology Genetics & Heredity gene essentiality prediction computational methods homology transposons next-generation sequencing MULTIPLE SEQUENCE ALIGNMENT GLOBAL TRANSPOSON MUTAGENESIS CLUSTAL-W GENOME IDENTIFICATION PHENOTYPE NETWORK RECONSTRUCTION LOCALIZATION OPTIMIZATION
Online Access:	http://hdl.handle.net/20.500.11937/80734

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