Inhibition of the lysophosphatidylinositol transporter abcc1 reduces prostate cancer cell growth and sensitizes to chemotherapy

Inhibition of the lysophosphatidylinositol transporter abcc1 reduces prostate cancer cell growth and sensitizes to chemotherapy

Expression of ATP-binding cassette (ABC) transporters has long been implicated in cancer chemotherapy resistance. Increased expression of the ABCC subfamily transporters has been reported in prostate cancer, especially in androgen-resistant cases. ABCC transporters are known to efflux drugs but, rec...

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Bibliographic Details
Main Authors: Emmanouilidi, Aikaterini, Casari, Ilaria, Akkaya, B.G., Maffucci, T., Furic, L., Guffanti, F., Broggini, M., Chen, X., Maxuitenko, Y.Y., Keeton, A.B., Piazza, G.A., Linton, K.J., Falasca, Marco
Format: Journal Article
Language:English
Published: 2020
Subjects:
ABC transporter
ABCC1/MRP1
Docetaxel
lysophosphatidylinositol
prostate cancer
Online Access:http://hdl.handle.net/20.500.11937/80686

Internet

http://hdl.handle.net/20.500.11937/80686

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