Exogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1

Exogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1

© 2020 Elsevier Inc. Cardiac fibrosis and myocyte hypertrophy are hallmarks of the cardiac remodelling process in cardiomyopathies such as heart failure (HF). Dyslipidemia or dysregulation of lipids contribute to HF. The dysregulation of high density lipoproteins (HDL) could lead to altered leve...

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Bibliographic Details
Main Authors: Magaye, R.R., Savira, F., Hua, Y., Xiong, X., Huang, L., Reid, Christopher, Flynn, B., Kaye, D., Liew, D., Wang, B.H.
Format: Journal Article
Language:English
Published: 2020
Subjects:
Cardiac remodelling
Dihydropshingosine 1 phosphate
JAK/STAT signalling
Sphingolipid
TIMP1
Online Access:http://purl.org/au-research/grants/nhmrc/1092642
http://hdl.handle.net/20.500.11937/80042

Internet

http://purl.org/au-research/grants/nhmrc/1092642
http://hdl.handle.net/20.500.11937/80042

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