Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

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Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

T-cell acute lymphoblastic leukemia (T-ALL) and T-cell acute lymphoblastic lymphoma (T-LBL) are aggressive hematological malignancies that are currently treated with high-dose chemotherapy. Over the last several years, the search toward novel and less-toxic therapeutic strategies for T-ALL/T-LBL pat...

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Bibliographic Details
Main Authors:	De Smedt, Renate, Morscio, Julie, Reunes, Lindy, Roels, Juliette, Bardelli, Valentina, Lintermans, Beatrice, Van Loocke, Wouter, Almeida, Afonso, Cheung, Laurence, Kotecha, Rishi, Mansour, Marc R, Uyttebroeck, Anne, Vandenberghe, Peter, La Starza, Roberta, Mecucci, Cristina, Lammens, Tim, Van Roy, Nadine, De Moerloose, Barbara, Barata, Joao T, Taghon, Tom, Goossens, Steven, Van Vlierberghe, Pieter
Format:	Journal Article
Language:	English
Published:	AMER SOC HEMATOLOGY 2020
Subjects:	Science & Technology Life Sciences & Biomedicine Hematology JAK/STAT PATHWAY INHIBITION TRANSCRIPTIONAL REGULATION SERINE/THREONINE KINASES PROTEIN-KINASES IL-7 RECEPTOR MURINE GROWTH PHOSPHORYLATION PROLIFERATION PROMOTER
Online Access:	http://purl.org/au-research/grants/nhmrc/1142627 http://hdl.handle.net/20.500.11937/79574

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