The EXACT protocol: A multi-centre, single-blind, randomised, parallel-group, controlled trial to determine whether early oxygen titration improves survival to hospital discharge in adult OHCA patients

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The EXACT protocol: A multi-centre, single-blind, randomised, parallel-group, controlled trial to determine whether early oxygen titration improves survival to hospital discharge in adult OHCA patients

Background: Experimental and observational research suggests hyperoxia following resuscitation from cardiac arrest is associated with neurological injury and worse clinical outcomes. This paper describes the rationale and design of the EXACT trial. EXACT aims to determine whether reducing oxygen in...

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Bibliographic Details
Main Authors:	Bray, Janet, Smith, K., Hein, C., Finn, Judith, Stephenson, M., Cameron, P., Stub, D., Perkins, G.D., Grantham, H., Bailey, P., Brink, D., Dodge, N., Bernard, S.
Format:	Journal Article
Language:	English
Published:	ELSEVIER IRELAND LTD 2019
Subjects:	Science & Technology Life Sciences & Biomedicine Critical Care Medicine Emergency Medicine General & Internal Medicine Oxygen Hyperoxia Out-of-hospital cardiac arrest Heart arrest Post-resuscitation care HEART-ASSOCIATION GUIDELINES CARDIAC-ARREST CARDIOPULMONARY-RESUSCITATION THERAPEUTIC HYPOTHERMIA REPERFUSION INJURY INDUCTION HYPEROXIA METAANALYSIS CARE
Online Access:	http://hdl.handle.net/20.500.11937/79488

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