The EXACT protocol: A multi-centre, single-blind, randomised, parallel-group, controlled trial to determine whether early oxygen titration improves survival to hospital discharge in adult OHCA patients

The EXACT protocol: A multi-centre, single-blind, randomised, parallel-group, controlled trial to determine whether early oxygen titration improves survival to hospital discharge in adult OHCA patients

Background: Experimental and observational research suggests hyperoxia following resuscitation from cardiac arrest is associated with neurological injury and worse clinical outcomes. This paper describes the rationale and design of the EXACT trial. EXACT aims to determine whether reducing oxygen in...

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Bibliographic Details
Main Authors: Bray, Janet, Smith, K., Hein, C., Finn, Judith, Stephenson, M., Cameron, P., Stub, D., Perkins, G.D., Grantham, H., Bailey, P., Brink, D., Dodge, N., Bernard, S.
Format: Journal Article
Language:English
Published: ELSEVIER IRELAND LTD 2019
Subjects:
Science & Technology
Life Sciences & Biomedicine
Critical Care Medicine
Emergency Medicine
General & Internal Medicine
Oxygen
Hyperoxia
Out-of-hospital cardiac arrest
Heart arrest
Post-resuscitation care
HEART-ASSOCIATION GUIDELINES
CARDIAC-ARREST
CARDIOPULMONARY-RESUSCITATION
THERAPEUTIC HYPOTHERMIA
REPERFUSION INJURY
INDUCTION
HYPEROXIA
METAANALYSIS
CARE
Online Access:http://hdl.handle.net/20.500.11937/79488

Internet

http://hdl.handle.net/20.500.11937/79488

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