CpG Methylation patterns in the IFN promoter in naive T cells: Variations during Th1 and Th2 differentiation and between atopics and non-atopics
Interferon- (IFN) gene expression is tightly regulated in early life, and exaggerated negative control of IFN production in CD4+ T cells has been associated with risk for subsequent development of atopy. Recent studies have demonstrated hypermethylation of CpG sites in the IFN promoter in neonates,...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Blackwell Publishing
2006
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| Online Access: | http://hdl.handle.net/20.500.11937/7829 |