Effect of iron chelators on proliferation and iron uptake in hepatoma cells

Effect of iron chelators on proliferation and iron uptake in hepatoma cells

Background. The siderophore desferrioxamine mesylate (DFO) is used routinely in clinical practice to treat diseases of iron (Fe) overload. Recent studies suggest that DFO and other chelators may have potential in the treatment of cancer. The current study reports the findings obtained when a number...

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Bibliographic Details
Main Authors: Kicic, Anthony, Chua, A.C.G., Baker, E.
Format: Journal Article
Language:English
Published: JOHN WILEY & SONS INC 2001
Subjects:
Science & Technology
Life Sciences & Biomedicine
Oncology
iron (Fe) chelators
hepatocellular carcinoma (HCC)
Fe metabolism
antineoplastic agents
chemotherapy
PYRIDOXAL ISONICOTINOYL HYDRAZONE
EFFECTIVE ANTIPROLIFERATIVE AGENTS
DNA-SYNTHESIS
HEPATOCELLULAR-CARCINOMA
CCL-39 CELLS
K562 CELLS
D-CECAT
DEFEROXAMINE
TRANSFERRIN
INHIBITION
Online Access:http://hdl.handle.net/20.500.11937/76837

Internet

http://hdl.handle.net/20.500.11937/76837

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