Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

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Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

Rationale: Damage to airway epitheliumis followed by deposition of extracellular matrix (ECM) and migration of adjacent epithelial cells. We have shown that epithelial cells from children with asthma fail to heal a wound in vitro. Objectives: To determine whether dysregulated ECM production by the e...

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Bibliographic Details
Main Authors:	Kicic, Anthony, Hallstrand, T.S., Sutanto, E.N., Stevens, P.T., Kobor, M.S., Taplin, C., Paré, P.D., Beyer, R.P., Stick, S.M., Knight, D.A.
Format:	Journal Article
Language:	English
Published:	AMER THORACIC SOC 2010
Subjects:	Science & Technology Life Sciences & Biomedicine Critical Care Medicine Respiratory System General & Internal Medicine fibronectin asthma epithelium wound repair inflammation OBSTRUCTIVE PULMONARY-DISEASE GROWTH-FACTOR RECEPTOR GENE-EXPRESSION AIRWAY EPITHELIUM INHALED CORTICOSTEROIDS BRONCHIAL EPITHELIUM IN-VIVO CELL-PROLIFERATION ALLERGEN CHALLENGE PEDIATRIC-AIRWAY
Online Access:	http://hdl.handle.net/20.500.11937/76818

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