Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair

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Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair

© 2015 Elsevier Ltd. The epithelium of asthmatics is characterized by reduced expression of E-cadherin and increased expression of the basal cell markers ck-5 and p63 that is indicative of a relatively undifferentiated repairing epithelium. This phenotype correlates with increased proliferation, com...

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Bibliographic Details
Main Authors:	Moheimani, F., Roth, H.M., Cross, J., Reid, A.T., Shaheen, F., Warner, S.M., Hirota, J.A., Kicic, Anthony, Hallstrand, T.S., Kahn, M., Stick, S.M., Hansbro, P.M., Hackett, T.L., Knight, D.A.
Format:	Journal Article
Language:	English
Published:	PERGAMON-ELSEVIER SCIENCE LTD 2015
Subjects:	Science & Technology Life Sciences & Biomedicine Biochemistry & Molecular Biology Cell Biology Airway epithelium beta-Catenin/CBP ICG-001 Epithelial-mesenchymal transition Wound repair SUBMUCOSAL GLAND MORPHOGENESIS ASTHMATIC EPITHELIUM DYSREGULATED REPAIR TUMOR-SUPPRESSOR PROTEIN CBP CELLS EXPRESSION FIBROSIS PATHWAY LUNG
Online Access:	http://hdl.handle.net/20.500.11937/76815

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